I switched to a new laptop a few weeks ago. It came with Vista. My first instinct was to reformat the hard disk and put back Windows XP. But I changed my mind and decided to try it.
I have not decided whether I like it or not. I am going to live with it for a while and see whether I like it. There were no major changes for things I normally do. There are a few pleasant surprises. I like the breadcrumbs interface in the explorer toolbar. Having been used to it in Plone and some of the wikis I use, it is nice to see it in the Document Explorer.